Ferrostatin 1 | Tocris Bioscience 5180/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ferrostatin 1

catalog :

5180/10

quantity :

10 mg (also 50 mg)

price :

229 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Bi J, Yang S, Li L, Dai Q, Borcherding N, Wagner B, et al. Metadherin enhances vulnerability of cancer cells to ferroptosis. Cell Death Dis. 2019;10:682 pubmed publisher

product information

brand :

Tocris

MasterCode :

5180

SKU :

5180/10

product name :

Ferrostatin 1

target :

Ferroptosis Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

262.35

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ferrostatin 1 is a selective inhibitor of erastin induced ferroptosis (EC50 = 60 nM). Specifically inhibits Ras selective lethal compound -induced death, but not cell death induced by other oxidative lethal compounds and apoptosis-inducing agents. Inhibits ferroptosis in cancer cells; also inhibits glutamate-induced cell death in organotypic rat brain slices. Prevents erastin induced accumulation of cytosolic and lipid reactive oxygen species.

extended description :

Selective inhibitor of erastin induced ferroptosis

chemical name text :

Ethyl 3-amino-4-(cyclohexylamino)benzoate

formula :

C 15 H 22 N 2 O 2

formula text :

C15H22N2O2

cas num :

347174-05-4

USD :

229 USD

product details :

Selective inhibitor of erastin induced ferroptosis

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage