ASP 7663 | Tocris Bioscience 5178 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ASP 7663

catalog :

5178

quantity :

10 mg (also 50 mg)

price :

212 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Blaha I, López Oliva M, Martínez M, Recio P, Agis Torres A, Martinez A, et al. Bladder Dysfunction in an Obese Zucker Rat: The Role of TRPA1 Channels, Oxidative Stress, and Hydrogen Sulfide. Oxid Med Cell Longev. 2019;2019:5641645 pubmed publisher
Ko M, Ganzen L, Coşkun E, Mukadam A, Leung Y, van Rijn R. A critical evaluation of TRPA1-mediated locomotor behavior in zebrafish as a screening tool for novel anti-nociceptive drug discovery. Sci Rep. 2019;9:2430 pubmed publisher

product information

brand :

Tocris

master code :

5178

SKU :

5178/10

product name :

ASP 7663

description :

Selective TRPA1 activator

target :

TRPA1 Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

263.26

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective TRPA1 activator (EC50 values are ~0.5 M in human, mouse and rat). Displays little or no affinity at more than 60 other related receptors, channels and enzymes. Stimulates 5-HT release from QGP-1 cells. Exhibits an abdominal analgesic effect in vivo . Orally bioavailable.

catalog number base :

5178

product keywords :

ASP7663 transient receptor potential ankyrin 1 selective TRPA1 activators activates anticonstipation abdominal analgesics 5HT TRPA1 5178,

extended description :

Selective TRPA1 activator

chemical name text :

(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid

formula :

C 14 H 14 FNO 3

formula text :

C14H14FNO3

cas num :

1190217-35-6

2020 USD :

203

2021 USD :

212 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage