product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
WZ 4003
catalog :
5177
quantity :
10 mg (also 50 mg)
price :
219 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
5177
SKU :
5177/10
product name :
WZ 4003
description :
Potent and selective NUAK1/2 inhibitor
target :
NUAK Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
496.99
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent and selective NUAK1/2 inhibitor (IC50 values are 20 and 100 nM respectively). Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members. Inhibits NUAK1-mediated MYPT1 phosphorylation. Also inhibits cell proliferation in U2OS cells.
catalog number base :
5177
product keywords :
WZ4003 potent selective NUAK1 inhibitors inhibits NUAK2 NUAK MYPT1 kinases NUAK 5177,
extended description :
Potent and selective NUAK1/2 inhibitor
chemical name text :
N-3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]propanamide
formula :
C 25 H 29 ClN 6 O 3
formula text :
C25H29ClN6O3
cas num :
1214265-58-3
2020 USD :
212
2021 USD :
219 USD
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK