ML 154 | Tocris Bioscience 5161 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 154

catalog :

5161

quantity :

10 mg (also 50 mg)

price :

264 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5161

SKU :

5161/10

product name :

ML 154

description :

Potent Neuropeptide S receptor antagonist

target :

Neuropeptide S Receptor Antagonist

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

545.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent neuropeptide S receptor (NPSR) antagonist (pA2 = 9.98). Inhibits neuropeptide S-induced ERK phosphorylation over cAMP responses and calcium responses (IC50 values are 9.3, 22.1 and 36.5 nM, respectively). Appears to modulate addictive behavior in vivo . Displays no activity against vasopressin V1B receptors. Brain penetrant.

catalog number base :

5161

product keywords :

ML154 Potent selective Neuropeptide S receptors NPSR antagonists ERK phosphorylation additive behaviour Blood brain barrier permeable Neuropeptide S Receptors 5161, Neuropeptide-S Receptor, NPSR1

extended description :

Potent Neuropeptide S receptor antagonist

chemical name text :

3-(Diphenylphosphinothioyl)-2-methyl-1-[(2E)-3-phenyl-2-propen-1-yl]imidazo[1,2-a]pyridinium bromide

formula :

C 29 H 26 N 2 PS.Br

formula text :

C29H26N2PS.Br

cas num :

1345964-89-7

2020 USD :

253

2021 USD :

264 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage