Medetomidine hydrochloride | Tocris Bioscience 5160/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Medetomidine hydrochloride

catalog :

5160/10

quantity :

10 mg (also 50 mg)

price :

190 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Furuta A, Asano K, Egawa S, de Groat W, Chancellor M, Yoshimura N. Role of alpha2-adrenoceptors and glutamate mechanisms in the external urethral sphincter continence reflex in rats. J Urol. 2009;181:1467-73 pubmed publisher
Moura E, Afonso J, Hein L, Vieira Coelho M. Alpha2-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice. Br J Pharmacol. 2006;149:1049-58 pubmed

product information

brand :

Tocris

MasterCode :

5160

SKU :

5160/10

product name :

Medetomidine hydrochloride

target :

Adrenergic alpha-2 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

236.74

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Medetomidine hydrochloride is a potent, highly selective 2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for 2- and 1-adrenoceptors respectively). Displays greater selectivity over 1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Active in vivo ; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. Active Isomer also available.

extended description :

Potent and highly selective 2 agonist

chemical name text :

4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride

formula :

C 13 H 16 N 2 .HCl

formula text :

C13H16N2.HCl

cas num :

86347-15-1

USD :

190 USD

product details :

Potent and highly selective 2 agonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage