SGI 1027 | Tocris Bioscience 5155/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SGI 1027

catalog :

5155/10

quantity :

10 mg (also 50 mg)

price :

247 USD

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5155

SKU :

5155/10

product name :

SGI 1027

Description :

DNA methyltransferase inhibitor

target :

DNA Methyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

461.52

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SGI 1027 is a DNA methyltransferase inhibitor. Inhibits the mammalian DNA methyltransferases DNMT3B, DNMT3A and DNMT1 (IC50 values are 7.5, 8 and 12.5 M with Poly(dl-dC) as the substrate). Reactivates silenced tumor suppressor genes by reducing CpG island hypermethylation.

extended description :

DNA methyltransferase inhibitor

chemical name text :

N-[4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide

formula :

C 27 H 23 N 7 O

formula text :

C27H23N7O

cas num :

1020149-73-8

USD :

247 USD

product details :

DNA methyltransferase inhibitor

storage :

Store at -20°C