ML 240 | Tocris Bioscience 5153/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 240

catalog :

5153/10

quantity :

10 mg (also 50 mg)

price :

243 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5153 - ML 240 C23H20N6O CAS No. 1346527-98-7

product information

brand :

Tocris

master code :

5153

SKU :

5153/10

rank :

0.061

product name :

ML 240

description :

ATP-competitive inhibitor of p97 ATPase

target :

Other ER Stress/UPR Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 240 is an ATP-competitive inhibitor of p97 ATPase (VCP, IC50 = 110 nM). Exhibits antiproliferative activity in NCI-60 cancer cell lines and rapidly induces executioner caspases 3 and 7 in multiple colon cancer cells. Promotes accumulation of LC3-II and impairs autophagosome maturation. Also impairs the endoplasmic-reticulum-associated degradation (ERAD) pathway.

extended description :

ATP-competitive inhibitor of p97 ATPase

chemical name text :

2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine

formula :

C 23 H 20 N 6 O

formula text :

C23H20N6O

cas num :

1346527-98-7

USD :

243 USD

product details :

ATP-competitive inhibitor of p97 ATPase

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage