NCL 00017509 | Tocris Bioscience 5150/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NCL 00017509

catalog :

5150/1

quantity :

1 mg

price :

287 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zhang X, Huang X, Xu J, Li E, Lao M, Tang T, et al. NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1. Nat Commun. 2021;12:4536 pubmed publisher

image

image 1 :

Cat.No. 5150 - NCL 00017509 C15H12N6O CAS No. 1507367-00-1

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5150

SKU :

5150/1

product name :

NCL 00017509

description :

Potent and reversible NIMA related kinase 2 (Nek2) inhibitor

target :

Nek2 Kinase Inhibitors

unit size :

1 mg

category :

Small Molecules

purity :

97%

storage :

Store at -20°C

observed molecular weight :

292.3

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NCL 00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo . In mice bearing pancreatic tumors, NCL 00017509 decreases PD-L1 expression and induces an anticancer immune response.

product keywords :

NCL00017509 NIMA related kinase 2 NEK2 inhibitors inhibits mitotic delay Nek2 Kinase 5150,

extended description :

Potent and reversible NIMA related kinase 2 (Nek2) inhibitor

chemical name text :

3-[(6-Ethynyl-9H-purin-2-yl)amino]benzeneacetamide

formula :

C15H12N6O

formula text :

C15H12N6O

cas num :

1507367-00-1

USD :

284

USD 2025 :

287 USD

product details :

Potent and reversible NIMA related kinase 2 (Nek2) inhibitor

more info or order :

Tocris Bioscience product webpage