Istradefylline | Tocris Bioscience 5147/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Istradefylline

catalog :

5147/10

quantity :

10 mg (also 50 mg)

price :

233 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
LaVigne J, Hecksel R, Keresztes A, Streicher J. Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity. Sci Rep. 2021;11:8232 pubmed publisher
Orr A, Lo I, Schumacher H, Ho K, Gill M, Guo W, et al. Istradefylline reduces memory deficits in aging mice with amyloid pathology. Neurobiol Dis. 2018;110:29-36 pubmed publisher
Cheng R, Segala E, Robertson N, Deflorian F, DorÃ© A, Errey J, et al. Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity. Structure. 2017;25:1275-1285.e4 pubmed publisher
Wydra K, Suder A, Borroto Escuela D, Filip M, Fuxe K. On the role of Aâ‚‚A and Dâ‚‚ receptors in control of cocaine and food-seeking behaviors in rats. Psychopharmacology (Berl). 2015;232:1767-78 pubmed publisher

product information

brand :

Tocris

MasterCode :

5147

SKU :

5147/10

product name :

Istradefylline

target :

Adenosine A2a Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

384.43

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Istradefylline is a potent and selective adenosine A2A receptor antagonist (Ki values are 2.2 and 150 nM for A2A and A1 receptors respectively). Anticataleptic and antiparkinson agent; reverses drug-induced motor dysfunction in animal models.

extended description :

Potent and selective A2A antagonist

chemical name text :

8-[(1E)-2-(2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione

formula :

C 20 H 24 N 4 O 4

formula text :

C20H24N4O4

cas num :

155270-99-8

USD :

233 USD

product details :

Potent and selective A2A antagonist

alt names :

KW-6002

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage