Propidium iodide | Tocris Bioscience 5135/10 product information

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company name :

Tocris Bioscience

product type :

chemical

product name :

Propidium iodide

catalog :

5135/10

quantity :

10 mg

price :

64 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Iram T, Ramirez Ortiz Z, Byrne M, Coleman U, Kingery N, Means T, et al. Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes. J Neurosci. 2016;36:5185-92 pubmed publisher
Kim Y, Ryu J, Ryu M, Lim S, Han K, Lim I, et al. C-reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B-cell translocation gene 2 expression. FEBS Lett. 2014;588:625-31 pubmed publisher

product information

brand :

Tocris

catalog number base :

5135

SKU :

5135/10

product name :

Propidium iodide

units size :

10 mg

description :

Red-fluorescent DNA stain, membrane impermeant to live cells. Used for: apoptosis detection, nuclear counterstaining, viability staining. Application: flow cytometry, confocal microscopy, fluorescence microscopy

target :

Fluorescent DNA Stains

category :

Small Molecules

purity :

95%

observed molecular weight :

668.39

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

review stars :

5

details of functionality :

Key information : Propidium iodide (PI) is a widely used red-fluorescent DNA stain. It is membrane impermeant to live cells and so PI staining differentiates live and dead cells. PI can be used to stain nucleic acids in dead cells across different cell types, including mammalian cells, bacteria, and yeast. . Application : flow cytometry, confocal microscopy, fluorescence microscopy. . Used for : apoptosis detection by PI staining, nuclear counterstaining in multicolor fluorescent assays, cell death measuring in a mixed live-cell population by PI staining and flow cytometry. . Properties and Photophysical Data : Propidium iodide fluorescence increases by approximately 20- to 30-fold upon binding to DNA or RNA (through intercalation). When unbound, excitation and emission maxima ( ) are 493 nm and 636 nm, respectively, when bound to DNA, excitation and emission maxima ( ) are 535 nm and 617 nm, respectively.

top caption :

Red-fluorescent DNA stain; membrane impermeant to live cells. Pi staining differentiates live and dead cells

applications :

Flow Cytometry

extended description :

Red-fluorescent DNA stain, membrane impermeant to live cells. Used for: apoptosis detection, nuclear counterstaining, viability staining. Application: flow cytometry, confocal microscopy, fluorescence microscopy

chemical name text :

3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide

formula :

C27H34I2N4

formula text :

C27H34I2N4

cas num :

25535-16-4

USD :

64 USD

product details :

Red-fluorescent DNA stain, membrane impermeant to live cells. Used for: apoptosis detection, nuclear counterstaining, viability staining. Application: flow cytometry, confocal microscopy, fluorescence microscopy

alt names :

PI

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage