This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
NAB 2
catalog :
5131/10
quantity :
10 mg (also 50 mg)
price :
256 USD
citations: 2
Reference
Amaral M, Goulart E, Caires Júnior L, Morales Vicente D, Soares Schanoski A, Gomes R, et al. Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins. PLoS Negl Trop Dis. 2020;14:e0008424 pubmed publisher
Caires Júnior L, Goulart E, Melo U, Araujo B, Alvizi L, Soares Schanoski A, et al. Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells. Nat Commun. 2018;9:475 pubmed publisher
product information
brand :
Tocris, a Bio-Techne Brand
catalog number base :
5131
SKU :
5131/10
product name :
NAB 2
Description :
Protects against -synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport
target :
Ubiquitin Ligase (E3) Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
389.88
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
NAB 2 protects against -synuclein toxicity. NAB 2 reverses the -synuclein-induced pathological phenotype in Parkinson s disease cortical neurons. NAB 2 promotes E3 ubiquitin ligase Rsp5/Nedd4-dependent endosomal transport.
extended description :
Protects against -synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport
chemical name text :
N-[(2-Chlorophenyl)methyl]-1-(2,5-dimethylphenyl)-1H-benzimidazole-5-carboxamide
formula :
C 23 H 20 ClN 3 O
formula text :
C23H20ClN3O
cas num :
1504588-00-4
USD :
256 USD
product details :
Protects against -synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport
storage :
Store at +4°C
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK