TC-G 1005 | Tocris Bioscience 5129/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-G 1005

catalog :

5129/10

quantity :

10 mg (also 50 mg)

price :

287 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Urso A, D Ovidio F, Xu D, Emala C, Bunnett N, Perez Zoghbi J. Bile acids inhibit cholinergic constriction in proximal and peripheral airways from humans and rodents. Am J Physiol Lung Cell Mol Physiol. 2020;318:L264-L275 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5129

SKU :

5129/10

product name :

TC-G 1005

Description :

Potent and selective GPBA receptor (TGR5) agonist

target :

GPBA Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

399.48

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-G 1005 is a potent and selective GPBA agonist (EC50 values are 0.72 nM and 6.2 nM for hTGR5 and mTGR5, respectively). TC-G 1005 is selective for TGR5 over FXR (farnesoid X receptor). TC-G 1005 increases plasma GLP-1 levels and reduces blood glucose in mice. Orally bioavailable.

extended description :

Potent and selective GPBA receptor (TGR5) agonist

chemical name text :

(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone

formula :

C 25 H 25 N 3 O 2

formula text :

C25H25N3O2

cas num :

1415407-60-1

USD :

287 USD

product details :

Potent and selective GPBA receptor (TGR5) agonist

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage