iMDK | Tocris Bioscience 5126/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

iMDK

catalog :

5126/10

quantity :

10 mg (also 50 mg)

price :

267 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Shin D, Jo J, Kim S, Choi M, Han C, Choi B, et al. Midkine Is a Potential Therapeutic Target of Tumorigenesis, Angiogenesis, and Metastasis in Non-Small Cell Lung Cancer. Cancers (Basel). 2020;12: pubmed publisher
Tsai S, Baselga Garriga C, Melton D. Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration. elife. 2020;9: pubmed publisher

product information

brand :

Tocris

catalog number base :

5126

SKU :

5126/10

product name :

iMDK

units size :

10 mg (also 50 mg)

description :

Suppressor of MDK expression; inhibits PI 3-K signaling

target :

Cytokine Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

376.4

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

iMDK is a suppressor of endogenous midkine (MDK) expression. Inhibits PI 3-K signaling in H441 lung adenocarcinoma cells. Selectively attenuates growth of MDK-expressing cancer cells. Induces apoptosis in H441 cells and suppresses growth of H441 cell xenografts in mice.

top caption :

Suppressor of MDK expression; inhibits PI 3-K signaling

extended description :

Suppressor of MDK expression; inhibits PI 3-K signaling

chemical name text :

3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one

formula :

C21H13FN2O2S

formula text :

C21H13FN2O2S

cas num :

881970-80-5

USD :

267 USD

product details :

Suppressor of MDK expression; inhibits PI 3-K signaling

storage :

Store at +4Â°C

more info or order :

Tocris Bioscience product webpage