3PO | Tocris Bioscience 5121/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

3PO

catalog :

5121/10

quantity :

10 mg (also 50 mg)

price :

121 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5121

SKU :

5121/10

product name :

3PO

description :

PFKFB3 inhibitor

target :

PFKFB3 Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at -20°C

observed molecular weight :

210.23

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

3PO is originally reported to inhibit PFKFB3 (IC50 = 25 M). More recent reports failed to demonstrate activity in a PFKFB3 kinase assay. Reduces glycolytic flux and suppresses glucose uptake. Inhibits endothelial cell proliferation and causes G2/M cell cycle arrest in vitro . Attenuates vessel sprouting and tumor growth in vivo . Amplifies the antiangiogenic effect of VEGFR blockade.

product keywords :

PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibitors inhibits glycolysis antitumor antitumour antiangiogenic Antiangiogenics PFKFB3 5121,

extended description :

PFKFB3 inhibitor

chemical name text :

3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one

formula :

C13H10N2O

formula text :

C13H10N2O

cas num :

13309-08-5

USD :

119

USD 2025 :

121 USD

product details :

PFKFB3 inhibitor

more info or order :

Tocris Bioscience product webpage