GSK 1562590 hydrochloride | Tocris Bioscience 5110/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 1562590 hydrochloride

catalog :

5110/10

quantity :

10 mg (also 50 mg)

price :

360 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5110 - GSK 1562590 hydrochloride C30H30Cl2N4O4.HCl CAS No. 1003878-07-6

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5110

SKU :

5110/10

product name :

GSK 1562590 hydrochloride

Description :

High affinity, selective urotensin II (UT) receptor antagonist

target :

Urotensin-II Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

617.95

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GSK 1562590 hydrochloride is a high affinity and selective urotensin II (UT) receptor antagonist (pKi values are 9.14, 9.28, 9.34, 9.64 and 9.66 at monkey, human, mouse, cat and rat recombinant receptors respectively). Exhibits selectivity for UT receptors over a range of GPCRs, ion channels, enzymes and neurotransmitter transporters. Supresses human urotensin-II (hU-II)-induced contraction of isolated rat aorta in vitro and ex vivo . Inhibits the hU-II-induced increase in mean blood pressure in vivo . Orally active.

extended description :

High affinity, selective urotensin II (UT) receptor antagonist

chemical name text :

N-[(1R)-1-[3 -(Aminocarbonyl)[1,1 -biphenyl]-4-yl]-2-(1-pyrrolidinyl)ethyl]-6,7-dichloro-2,3-dihydro-N-methyl-3-oxo-4H-1,4-benzoxazine-4-acetamide hydrochloride

formula :

C 30 H 30 Cl 2 N 4 O 4 .HCl

formula text :

C30H30Cl2N4O4.HCl

cas num :

1003878-07-6

USD :

360 USD

product details :

High affinity, selective urotensin II (UT) receptor antagonist

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage