product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SB 743921 hydrochloride
catalog :
5109/10
quantity :
10 mg (also 50 mg)
price :
249 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
catalog number base :
5109
SKU :
5109/10
product name :
SB 743921 hydrochloride
units size :
10 mg (also 50 mg)
description :
Potent kinesin spindle protein (KSP) inhibitor
target :
Kinesin Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
553.52
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SB 743921 hydrochloride is a potent kinesin spindle protein (KSP) inhibitor (Ki = 0.1 nM). Induces cell mitotic arrest and apoptosis in vitro . Inhibits the growth of a range of tumor cells in vitro , including colon (HCT 116), prostate (PC-3) and leukemia (K-562) cancer cell lines. Causes tumor regression in human tumor xenograft models in vivo , including colon (Colo205), lung (H69) and breast (MCF7) cancer cell xenografts.
top caption :
Potent kinesin spindle protein (KSP) inhibitor
extended description :
Potent kinesin spindle protein (KSP) inhibitor
chemical name text :
N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4H-1-benzopyran-2-yl]-2-methylpropyl]-4-methylbenzamide hydrochloride
formula :
C31H33ClN2O3.HCl
formula text :
C31H33ClN2O3.HCl
cas num :
940929-33-9
USD :
249 USD
product details :
Potent kinesin spindle protein (KSP) inhibitor
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK