TFC 007 | Tocris Bioscience 5108/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TFC 007

catalog :

5108/10

quantity :

10 mg (also 50 mg)

price :

197 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5108

SKU :

5108/10

product name :

TFC 007

Description :

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

target :

Synthase/Synthetase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

487.55

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TFC 007 is a potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor (IC50 = 83 nM). Inhibits PGD2 production and late phase nasal blockage in an animal model of allergic rhinitis. Exhibits negligible effects on COX-1, COX-2, 5-LOX, LTC4 synthase, TXA2 synthase and microsomal prostaglandin E2 synthase.

extended description :

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

chemical name text :

N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide

formula :

C 27 H 29 N 5 O 4

formula text :

C27H29N5O4

cas num :

927878-49-7

USD :

197 USD

product details :

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage