chemical

PLX 647 dihydrochloride

5102

10 mg (also 50 mg)

147 USD

5102

5102/10

PLX 647 dihydrochloride

Potent dual Fms/KIT inhibitor

Additional RTK Inhibitors

Small Molecules

10 mg (also 50 mg)

97%

455.3

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Potent dual KIT/Fms inhibitor (IC50 values are 16 and 28 nM respectively). Inhibits BCR-FMS cell proliferation and osteoclast differentiation in vitro (IC50 values are 92 and 170 nM respectively). Attenuates LPS-induced TNF and IL-6 release, mast cell activation and macrophage kidney proliferation in vivo .

5102

PLX647 dihydrochloride potent selective FMS KIT dual inhibitors kinases proliferation antiproliferative differentiation osteoclasts inhibits Other RTKs 5102,

Potent dual Fms/KIT inhibitor

5-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-2-pyridinamine dihydrochloride

C 21 H 17 F 3 N 4 .2HCl

C21H17F3N4.2HCl

1779796-38-1

147

147 USD

Store at -20°C