KRCA 0008 | Tocris Bioscience 5098/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KRCA 0008

catalog :

5098/10

quantity :

10 mg (also 50 mg)

price :

158 USD

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5098

SKU :

5098/10

product name :

KRCA 0008

Description :

Potent Ack1 and ALK dual inhibitor; orally bioavailable

target :

ALK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

609.12

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

KRCA 0008 is a potent Ack1 and anaplastic lymphoma kinase (ALK) dual inhibitor (IC50 values are 4 and 12 nM respectively). Inhibits lung cancer H3122 cell proliferation (IC50 = 80 nM). Attenuates H3122 cell xenograft tumor growth in mice. Orally bioavailable.

extended description :

Potent Ack1 and ALK dual inhibitor; orally bioavailable

chemical name text :

1,1 -[(5-Chloro-2,4-pyrimidinediyl)bis[imino(3-methoxy-4,1-phenylene)-4,1-piperazinediyl]]bisethanone

formula :

C 30 H 37 ClN 8 O 4

formula text :

C30H37ClN8O4

cas num :

1472795-20-2

USD :

158 USD

product details :

Potent Ack1 and ALK dual inhibitor; orally bioavailable

storage :

Store at -20°C