TC-E 5002 | Tocris Bioscience 5089/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-E 5002

catalog :

5089/10

quantity :

10 mg (also 50 mg)

price :

282 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Drosos Y, Myers J, Xu B, Mathias K, Beane E, Radko Juettner S, et al. NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition. Mol Cell. 2022;82:2472-2489.e8 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5089

SKU :

5089/10

product name :

TC-E 5002

Description :

Selective KDM2/7 inhibitor

target :

Histone Demethylase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

285.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-E 5002 is a selective histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.2, 1.2, 6.8, 55, 83, 100 and 120 M for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). Inhibits growth of HeLa and KYSE-150 cancer cells in vitro .

extended description :

Selective KDM2/7 inhibitor

chemical name text :

N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy- -alanine

formula :

C 15 H 27 NO 4

formula text :

C15H27NO4

cas num :

1453071-47-0

USD :

282 USD

product details :

Selective KDM2/7 inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage