PA 452 | Tocris Bioscience 5086/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PA 452

catalog :

5086/10

quantity :

10 mg (also 50 mg)

price :

328 USD

citations: 2

Reference
Yuan L, Liu X, Zhang L, Li X, Zhang Y, Wu K, et al. A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cell for the Chronic Hepatitis B Virus Infection. Front Microbiol. 2018;9:908 pubmed publisher
Wang B, Fu X, Zhu M, Du M. Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation. J Mol Cell Biol. 2017;9:338-349 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5086

SKU :

5086/10

product name :

PA 452

Description :

RXR antagonist

target :

Retinoid X Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

439.59

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PA 452 is an RXR antagonist (pA2 = 7.11). Triggers dissociation of RXR tetramers. Attenuates cell proliferation and induces apoptosis in MCF-7 breast cancer cells.

extended description :

RXR antagonist

chemical name text :

2-[[3-(Hexyloxy)-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl]methylamino]-5-pyrimidinecarboxylic acid

formula :

C 26 H 37 N 3 O 3

formula text :

C26H37N3O3

cas num :

457657-34-0

USD :

328 USD

product details :

RXR antagonist

storage :

Store at +4°C