ABT 089 dihydrochloride | Tocris Bioscience 5079 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ABT 089 dihydrochloride

catalog :

5079

quantity :

10 mg (also 50 mg)

price :

171 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5079

SKU :

5079/10

product name :

ABT 089 dihydrochloride

description :

High affinity and selective 4 2 nAChR partial agonist

target :

Nicotinic (a4b2) Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

265.18

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity and selective 4 2 partial agonist (Ki = 16 nM). Exhibits 1000-fold and 10,000-fold selectivity for 4 2 over 1 1 1 and 7 receptors respectively. Neuroprotective against glutamate-induced toxicity in rat cortical neurons in vitro . Enhances cognitive performance in vivo . Orally bioavailable and brain penetrant.

catalog number base :

5079

product keywords :

ABT089 dihydrochloride high affinity selective a4b2 alpha4beta2 4 2 partial agonists neuroprotective brain penetrant orally bioavailable cholinergic receptors channels Nicotinic (a4b2) Receptors 5079,

extended description :

High affinity and selective 4 2 nAChR partial agonist

chemical name text :

2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride

formula :

C 11 H 16 N 2 O.2HCl

formula text :

C11H16N2O.2HCl

cas num :

161416-61-1

2020 USD :

189

2021 USD :

171 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage