Harmine | Tocris Bioscience 5075 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Harmine

catalog :

5075

quantity :

50 mg

price :

63 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Singh S, Janjuha S, Hartmann T, Kayisoglu Ö, Konantz J, Birke S, et al. Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth. Nat Commun. 2017;8:664 pubmed publisher

product information

brand :

Tocris

master code :

5075

SKU :

5075/50

product name :

Harmine

description :

Potent and selective DYRK1A inhibitor

target :

DYRK Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

212.25

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective inhibitor of DYRK1A (IC50 values are 80, 800 and 900 nM for DYRK1A, DYRK3 and DYRK2 respectively). Inhibits DYRK1A-mediated tau phosphorylation and regulates PPAR expression. Also induces pancreatic beta cell proliferation. Exhibits antidiabetic activity. Orally bioavailable.

catalog number base :

5075

product keywords :

Harmine dyrk1a dyrk inhibitors inhibits potent selective dual specificity tyrosine phosphorylation regulated kinase-1A PPARg PPARgamma PPAR antidiabetic Microtubules DYRK 5075,

extended description :

Potent and selective DYRK1A inhibitor

chemical name text :

7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole

formula :

C 13 H 12 N 2 O

formula text :

C13H12N2O

cas num :

442-51-3

2020 USD :

2021 USD :

63 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage