Teriflunomide | Tocris Bioscience 5069 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Teriflunomide

catalog :

5069

quantity :

50 mg

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Styr B, Gonen N, Zarhin D, Ruggiero A, Atsmon R, Gazit N, et al. Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility. Neuron. 2019;102:1009-1024.e8 pubmed publisher

product information

brand :

Tocris

master code :

5069

SKU :

5069/50

product name :

Teriflunomide

description :

Inhibitor of DHODH; active metabolite of Leflunomide

target :

Dehydrogenase Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

270.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of dihydroorotate dehydrogenase (Kd = 12 nM; Ki = 179 nM). Inhibits proliferation of mitogen- or cytokine-stimulated lymphoid cells in vitro by inhibiting cell cycle progression from G1 to S. Imunosuppressive agent. Active metabolite of leflunomide (Cat. No. 2228).

catalog number base :

5069

product keywords :

Active metabolite leflunomide A771726 A 77-1726 A 771226 A77 1726 dihydroorolate dehydrogenase inhibitors inhibits immunosuppressive agent drug immunomodulatory A77 1726 Immunosuppressants Dihyroorotate Dehydrogenase DNA, RNA and Protein Synthesis 5069, DHODH Inhibitor, Dihydroorotate Dehydrogenase Inhibitor, Dihydroorotate Dehydrogenase Inhibitors, Dihydroorotate Oxidase, DHOdehase, POADS, URA1

extended description :

Inhibitor of DHODH; active metabolite of Leflunomide

chemical name text :

2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide

formula :

C 12 H 9 F 3 N 2 O 2

formula text :

C12H9F3N2O2

cas num :

108605-62-5

2020 USD :

145

2021 USD :

151 USD

alt names :

A77 1726

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage