Teriflunomide | Tocris Bioscience 5069/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Teriflunomide

catalog :

5069/50

quantity :

50 mg

price :

189 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Zarhin D, Atsmon R, Ruggiero A, Baeloha H, Shoob S, Scharf O, et al. Disrupted neural correlates of anesthesia and sleep reveal early circuit dysfunctions in Alzheimer models. Cell Rep. 2022;38:110268 pubmed publisher
Styr B, Gonen N, Zarhin D, Ruggiero A, Atsmon R, Gazit N, et al. Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility. Neuron. 2019;102:1009-1024.e8 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5069

SKU :

5069/50

product name :

Teriflunomide

Description :

Inhibitor of DHODH; active metabolite of Leflunomide

target :

DHODH Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

270.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Teriflunomide is an inhibitor of dihydroorotate dehydrogenase (Kd = 12 nM; Ki = 179 nM). Inhibits proliferation of mitogen- or cytokine-stimulated lymphoid cells in vitro by inhibiting cell cycle progression from G1 to S. Immunosuppressive agent. Active metabolite of leflunomide.

extended description :

Inhibitor of DHODH; active metabolite of Leflunomide

chemical name text :

2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide

formula :

C 12 H 9 F 3 N 2 O 2

formula text :

C12H9F3N2O2

cas num :

108605-62-5

USD :

189 USD

product details :

Inhibitor of DHODH; active metabolite of Leflunomide

alt names :

A77 1726

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage