ANAVEX 2-73 | Tocris Bioscience 5058/50 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

ANAVEX 2-73

catalog :

5058/50

quantity :

50 mg

price :

695 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

CN(CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)OCC1)C.Cl

Stock Reference :

5058/50

Cat Number :

5058

Product Name :

ANAVEX 2-73

Cas Number :

[195615-84-0]

Unit Size :

50 mg

Size :

Unit :

USD :

695 USD

Primary Category :

Other Pharmacology

Secondary Category :

Sigma Receptors

Tertiary Category :

Sigma1 Receptors

Primary Action :

Mixed ?1 and muscarinic receptor agonist; exhibits neuroprotective effects

Biological Description :

?1 agonist (IC50 = 860 nM); also displays affinity for muscarinic M1-M4 receptors (Ki values < 500 nM), but not for ?2 receptors. Exhibits neuroprotective effects, prevents tau hyperphosphorylation, and attenuates scopolamine- and (+)-MK 801-induced learning deficits in a mouse model of amyloid toxicity.

Storage :

Store at RT

Formula :

C19H23NO.HCl

Molwt :

317.85

Minimum Purity :

> 98%

Solubility :

Soluble to 100 mM in water and to 100 mM in DMSO

RTECS No :

Not available

more info or order :

Tocris Bioscience product webpage