Ki 16425 | Tocris Bioscience 5056 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ki 16425

catalog :

5056

quantity :

25 mg

price :

389 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Evseenko D, Latour B, Richardson W, Corselli M, Sahaghian A, Cardinal S, et al. Lysophosphatidic acid mediates myeloid differentiation within the human bone marrow microenvironment. PLoS ONE. 2013;8:e63718 pubmed publisher

product information

brand :

Tocris

master code :

5056

SKU :

5056/25

product name :

Ki 16425

description :

LPA1 and LPA3 receptor antagonist

target :

Lysophosphatidic Acid (LPA) Receptor Antagonists

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

474.96

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antagonist of the lysophosphatidic acid receptors LPA1 and LPA3 (Ki values are 0.25 and 0.36 M respectively, in a GTP S binding assay). Blocks LPA-induced dephosphorylation of Yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (TAZ), inhibiting the Hippo signaling pathway, in HEK293A cells.

catalog number base :

5056

product keywords :

Ki16425 lysophosphatidic acid receptors LPA1 LPA2 LPA3 YAP TAZ HIPPO Lysophosphatidic Acid Receptors Hippo/Yap signaling 5056,

extended description :

LPA1 and LPA3 receptor antagonist

chemical name text :

3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid

formula :

C 23 H 23 ClN 2 O 5 S

formula text :

C23H23ClN2O5S

cas num :

355025-24-0

2020 USD :

374

2021 USD :

389 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage