product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CASIN
catalog :
5050
quantity :
10 mg
price :
229 USD
more info or order :
citations: 1
Reference
Cheng Q, Sedlic F, Pravdic D, Bosnjak Z, Kwok W. Biphasic effect of nitric oxide on the cardiac voltage-dependent anion channel. FEBS Lett. 2011;585:328-34 pubmed publisher
product information
brand :
Tocris
master code :
5050
SKU :
5050/10
product name :
CASIN
description :
Cdc42 inhibitor
target :
Rho GTPase Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
306.4
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cdc42 GTPase inhibitor (IC50 = 2 M). Reduces active levels of Cdc42 in aged hematopoietic stem cells (HSCs) to that in young HSCs. Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo . Increases histone H4K16 acetylation in aged HSCs.
catalog number base :
5050
product keywords :
Cdc42 GTPase inhibitors inhibits hematopoietic stem cells HSCs aged young stem cell signaling Stem Cell Signaling Rho 5050,
extended description :
Cdc42 inhibitor
chemical name text :
2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol
formula :
C 20 H 22 N 2 O
formula text :
C20H22N2O
cas num :
425399-05-9
2020 USD :
222
2021 USD :
229 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK