CASIN | Tocris Bioscience 5050/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CASIN

catalog :

5050/10

quantity :

10 mg

price :

288 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Endo Y, Hickerson B, Ilyushina N, Mohan N, Peng H, Takeda K, et al. Identification of a pharmacological approach to reduce ACE2 expression and development of an in vitro COVID-19 viral entry model. J Virus Erad. 2022;8:100307 pubmed publisher
Weeber F, Becher A, Seibold T, Seufferlein T, Eiseler T. Concerted regulation of actin polymerization during constitutive secretion by cortactin and PKD2. J Cell Sci. 2019;132: pubmed publisher
Cheng Q, Sedlic F, Pravdic D, Bosnjak Z, Kwok W. Biphasic effect of nitric oxide on the cardiac voltage-dependent anion channel. FEBS Lett. 2011;585:328-34 pubmed publisher

product information

brand :

Tocris

catalog number base :

5050

SKU :

5050/10

product name :

CASIN

units size :

10 mg

description :

Cdc42 inhibitor

target :

Rho GTPase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

306.4

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CASIN is a Cdc42 GTPase inhibitor (IC50 = 2 M). Reduces active levels of Cdc42 in aged hematopoietic stem cells (HSCs) to that in young HSCs. Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo . Increases histone H4K16 acetylation in aged HSCs.

top caption :

Cdc42 inhibitor

extended description :

Cdc42 inhibitor

chemical name text :

2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol

formula :

C20H22N2O

formula text :

C20H22N2O

cas num :

425399-05-9

USD :

288 USD

product details :

Cdc42 inhibitor

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage