LM11A 31 dihydrochloride | Tocris Bioscience 5046 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LM11A 31 dihydrochloride

catalog :

5046

quantity :

10 mg (also 50 mg)

price :

117 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5046

SKU :

5046/10

product name :

LM11A 31 dihydrochloride

description :

Nonpeptide p75NTR ligand; neuroprotective

target :

Trk Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

95%

observed molecular weight :

316.27

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Nonpeptide p75NTR ligand; blocks p75-mediated cell death and also increases proliferation and survival of hippocampal neural progenitors. Exhibits no effect on nerve growth factor (NGF) binding to TrkA. Prevents and reverses atrophy of cholinergic neurites, as well as reversing Alzheimer s Disease (AD) pathologies in mid- to late-stage AD mice models. Shown to promote functional recovery in a mouse model of spinal cord injury. Orally available and brain penetrant.

catalog number base :

5046

product keywords :

LM11A31 dihydrochloride p75NTR ligands selective NGFR nerve growth factor receptors Alzheimer's Disease neuroprotective Trk Receptors Neuronal Metabolism 5046,

extended description :

Nonpeptide p75NTR ligand; neuroprotective

chemical name text :

(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride

formula :

C 12 H 25 N 3 O 2 .2HCl

formula text :

C12H25N3O2.2HCl

cas num :

1243259-19-9

2020 USD :

112

2021 USD :

117 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage