product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Psalmotoxin 1
catalog :
5042/100U
quantity :
100 ug
price :
335 USD
more info or order :
citations: 2
Reference
Lim J, Tai H, Liao W, Chu Y, Hao C, Huang Y, et al. ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain. elife. 2021;10: pubmed publisher
King P, Wan J, Guo A, Guo S, Jiang Y, Liu M. Regulation of gliomagenesis and stemness through acid sensor ASIC1a. Int J Oncol. 2021;59: pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
5042
SKU :
5042/100U
product name :
Psalmotoxin 1
description :
Potent and selective ASIC1a channel blocker
target :
Acid-sensing Ion Channel Blockers
unit size :
100 ug
category :
Peptides
purity :
95%
storage :
Store at -20°C
observed molecular weight :
4689.41
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Psalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker (IC50 = 0.9 nM). Displays no effect at ASIC1b, ASIC2a, ASIC3, heteromeric ASIC channels, ENaC and KV2.1/2.2/4.2/4.3 channels expressed in oocytes, at concentrations up to 100 nM. Displays potent analgesic properties against thermal, mechanical, chemical, inflammatory and neuropathic pain in rodents.
product keywords :
pctx1 acid-sensing acid ion channel 1a ASIC1a ASIC blockers analgesic pain thermal mechanical chemical inflammatory neuropathic venoms PcTx1 ASIC 5042,
extended description :
Potent and selective ASIC1a channel blocker
formula :
C200H312N62O57S6
formula text :
C200H312N62O57S6
cas num :
316808-68-1
USD :
331
USD 2025 :
335 USD
product details :
Potent and selective ASIC1a channel blocker
alt names :
PcTx1
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK