Nepicastat hydrochloride | Tocris Bioscience 5037 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Nepicastat hydrochloride

catalog :

5037

quantity :

10 mg (also 50 mg)

price :

156 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5037

SKU :

5037/10

product name :

Nepicastat hydrochloride

description :

Potent and selective dopamine -hydroxylase (DBH) inhibitor; orally bioavailable

target :

Hydroxylase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

331.81

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective dopamine -hydroxylase (DBH) inhibitor (IC50 = 9 nM) . Selective for DBH over 12 other enzymes. Decreases noradrenaline and increases dopamine levels in tissues and plasma in hypertensive rats. Prevents progressive left ventricular dysfunction in an in vivo heart failure model. Also potentiates the stimulus effects of cocaine without producing cocaine-like effects in rats. Orally bioavailable.

catalog number base :

5037

product keywords :

dopamine beta-hydroxylase inhibitors inhibits B-hydroxylase DBH noradrenaline norepinephrine potent selective orally bioavailable DBH Hydroxylases 5037,

extended description :

Potent and selective dopamine -hydroxylase (DBH) inhibitor; orally bioavailable

chemical name text :

5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride

formula :

C 14 H 15 F 2 N 3 S.HCl

formula text :

C14H15F2N3S.HCl

cas num :

170151-24-3

2020 USD :

173

2021 USD :

156 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage