CHC | Tocris Bioscience 5029 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CHC

catalog :

5029

quantity :

50 mg

price :

63 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Jang C, Oh S, Wada S, Rowe G, Liu L, Chan M, et al. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016;22:421-6 pubmed publisher

product information

brand :

Tocris

master code :

5029

SKU :

5029/50

product name :

CHC

description :

MCT inhibitor; decreases glycoloysis

target :

Monocarboxylate Transporter Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

189.17

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Monocarboxylic acid transport (MCT) inhibitor. Exhibits antitumoral and antiangiogenic activity in gliomas in vivo ; decreases glycolytic metabolism, migration, and invasion in U251 cells. Enhances the effect of antitumor agent temozolomide (Cat No. 2706). Blocks lactate efflux from glioma cells and sensitizes cells to irradiation.

catalog number base :

5029

product keywords :

a-cyano-4-OH-cinnamate alpha-cyano-4-OH-cinnamate CHC monocarboxylic acid monocarboxylate transporters MCT inhibitors inhibits lactate pyruvate glycolytic metabolism gliomas antiangiogenesis antitumoral ACCA ?-cyano-4-hydroxy-cinnamic acid Antiangiogenics Monocarboxylate Transporters 5029,

extended description :

MCT inhibitor; decreases glycoloysis

chemical name text :

2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid

formula :

C 10 H 7 NO 3

formula text :

C10H7NO3

cas num :

28166-41-8

2020 USD :

2021 USD :

63 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage