chemical

BMS 599626 dihydrochloride

5022

10 mg

210 USD

5022

5022/10

BMS 599626 dihydrochloride

Potent, selective EGFR and ErbB2 inhibitor

EGF Receptor Inhibitors

Small Molecules

10 mg

98%

603.48

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

Potent and selective EGFR and ErbB2 inhibitor (IC50 values are 22 nM and 32 nM respectively). Also inhibits HER4 (IC50 = 190 nM). Inhibits EGFR and ErbB2 with 100-fold greater potency than MEK and Lck. Antiproliferative agent in vitro and anti-tumorigenic agent in vivo . Orally bioavailable.

5022

BMS599626 potent selective HER1 HER2 EGFR erbB-2 erbB2 tyrosine kinase inhibitors inhibits kinases receptors growth factor Neu antitumor antitumour antiproliferative EGFR 5022,

Potent, selective EGFR and ErbB2 inhibitor

(3S)-3-Morpholinylmethyl-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamate dihydrochloride

C 27 H 27 FN 8 O 3 .2HCl

C27H27FN8O3.2HCl

1781932-33-9

210

210 USD

Store at -20°C