product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Fisetin
catalog :
5016/50
quantity :
50 mg
price :
80 USD
more info or order :
citations: 4
Reference
Park J, Sohn H, Koh Y, Jo C. A splicing variant of TFEB negatively regulates the TFEB-autophagy pathway. Sci Rep. 2021;11:21119 pubmed publisher
Carriba P, Davies A. Signalling Pathways Mediating the Effects of CD40-Activated CD40L Reverse Signalling on Inhibitory Medium Spiny Neuron Neurite Growth. Cells. 2021;10: pubmed publisher
Carriba P, Davies A. How CD40L reverse signaling regulates axon and dendrite growth. Cell Mol Life Sci. 2021;78:1065-1083 pubmed publisher
Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed publisher
product information
brand :
Tocris, a Bio-Techne Brand
catalog number base :
5016
SKU :
5016/50
product name :
Fisetin
Description :
Naturally occuring flavonoid and antioxidant; neuroprotective
target :
Additional Antioxidant Compounds
category :
Small Molecules
unit size :
50 mg
purity :
97%
observed molecular weight :
286.24
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Fisetin is a naturally occuring flavonoid and antioxidant. Inhibits PI 3-K, Akt, mTOR and Cdk6. Displays antiproliferative activity in prostate cancer cells. Shown to activate ERK; exhibits neuroprotective activity in Huntington s disease models. Also a DNMT1 inhibitor.
extended description :
Naturally occuring flavonoid and antioxidant; neuroprotective
chemical name text :
2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
formula :
C 15 H 10 O 6
formula text :
C15H10O6
cas num :
528-48-3
USD :
80 USD
product details :
Naturally occuring flavonoid and antioxidant; neuroprotective
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK