HMR 1556 | Tocris Bioscience 5011/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HMR 1556

catalog :

5011/10

quantity :

10 mg

price :

292 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5011 - HMR 1556 C17H24F3NO5S CAS No. 223749-46-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5011

SKU :

5011/10

product name :

HMR 1556

description :

Potent and selective Iks channel blocker

target :

Voltage-gated Potassium Channel Blockers

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

411.44

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

HMR 1556 is a potent and selective Iks channel blocker (IC50 values are 10.5 and 34 nM in canine and guinea pig ventricular myocytes respectively). Selectively inhibits IKs currents over IKr, IKI, Ito and L-type Ca2+ channel currents. Also has little or no effect on Kv11.1 Kv1.5, Kv1.3, Kir2.1 and HCN2 channel currents. Potentiates E-4031 -induced arrhythmias in vivo .

product keywords :

HMR1556 potent selective IKs channels blockers blocks cardiac Kv7.1 potassium K+ slow delayed rectifier current KCNQ1 voltage-gated voltage-dependent Voltage-Gated Potassium Channels 5011,

extended description :

Potent and selective Iks channel blocker

chemical name text :

N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide

formula :

C17H24F3NO5S

formula text :

C17H24F3NO5S

cas num :

223749-46-0

USD :

283

USD 2025 :

292 USD

product details :

Potent and selective Iks channel blocker

more info or order :

Tocris Bioscience product webpage