Rhosin hydrochloride | Tocris Bioscience 5003 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Rhosin hydrochloride

catalog :

5003

quantity :

10 mg (also 50 mg)

price :

108 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5003

SKU :

5003/10

product name :

Rhosin hydrochloride

description :

Rho inhibitor

target :

Rho GTPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

394.86

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Has no effect on the binding of Rac1 or Cdc42 to their respective GEFs. Suppresses RhoA/C-mediated breast cancer cell migration and invasion in vitro . Also induces neurite outgrowth in synergy with NGF.

catalog number base :

5003

product keywords :

Rho GTPases inhibitors inhibits guanine nucleotide exchange factors GEF Rho 5003,

extended description :

Rho inhibitor

chemical name text :

D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride

formula :

C 20 H 18 N 6 O.HCl

formula text :

C20H18N6O.HCl

cas num :

1281870-42-5

2020 USD :

103

2021 USD :

108 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage