FTIDC | Tocris Bioscience 5000/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FTIDC

catalog :

5000/10

quantity :

10 mg

price :

420 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5000

SKU :

5000/10

product name :

FTIDC

Description :

Potent and selective negative allosteric modulator of mGlu1 receptors; also mGlu1 inverse agonist

target :

Group I mGluR Modulators

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

358.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

FTIDC is a potent and selective mGlu1 receptor negative allosteric modulator (IC50 values are 5.8 and 6200 nM for mGlu1 and mGlu5 respectively). Also acts as an mGlu1 receptor inverse agonist (IC50 = 7 nM) in the absence of ligand. Exhibits no effect at group II/III mGlu receptors. Inhibits L-glutamate-induced increases in intracellular calcium in mGlu1-expressing CHO cells. Inhibits nociceptive behavior, and exhibits anxiolytic and antipsychotic effects in vivo . Orally active.

extended description :

Potent and selective negative allosteric modulator of mGlu1 receptors; also mGlu1 inverse agonist

chemical name text :

4-[1-(2-Fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-3,6-dihydro-N-methyl-N-(1-methylethyl)-1(2H)-pyridinecarboxamide

formula :

C 18 H 23 FN 6 O

formula text :

C18H23FN6O

cas num :

873551-53-2

USD :

420 USD

product details :

Potent and selective negative allosteric modulator of mGlu1 receptors; also mGlu1 inverse agonist

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage