9-Phenanthrol | Tocris Bioscience 4999 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

9-Phenanthrol

catalog :

4999

quantity :

50 mg

price :

63 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
O Malley J, Seibt F, Chin J, Beierlein M. TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations. J Neurosci. 2020;40:4813-4823 pubmed publisher
Lin E, Combe C, Gasparini S. Differential Contribution of Ca2+-Dependent Mechanisms to Hyperexcitability in Layer V Neurons of the Medial Entorhinal Cortex. Front Cell Neurosci. 2017;11:182 pubmed publisher

product information

brand :

Tocris

master code :

4999

SKU :

4999/50

product name :

9-Phenanthrol

description :

Selective TRPM4 blocker

target :

TRPM Agonists

category :

Small Molecules

unit size :

50 mg

observed molecular weight :

194.23

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective TRPM4 blocker (IC50 = 20 M in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). Abolishes arrhythmias induced by hypoxia in a mouse heart model.

catalog number base :

4999

product keywords :

Transient receptor potential TRPM4 blockers TRP channels arrhythmias cardiac heart anti-arrhythmic depolarisations TRPM 4999,

extended description :

Selective TRPM4 blocker

chemical name text :

9-Hydroxyphenanthrene

formula :

C 14 H 10 O

formula text :

C14H10O

cas num :

484-17-3

2020 USD :

2021 USD :

63 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage