ProINDY | Tocris Bioscience 4998 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ProINDY

catalog :

4998

quantity :

10 mg

price :

189 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Kim H, Lee K, Kim A, Choi M, Choi K, Kang M, et al. A chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibition. Dis Model Mech. 2016;9:839-48 pubmed publisher
Seu L, Sabbaj S, Duverger A, Wagner F, Anderson J, Davies E, et al. Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection. J Virol. 2015;89:6656-72 pubmed publisher

product information

brand :

Tocris

master code :

4998

SKU :

4998/10

product name :

ProINDY

description :

DYRK1A/B inhibitor; prodrug of INDY (Cat. No. 4997)

target :

DYRK Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

277.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DYRK1A/B inhibitor; prodrug form of INDY (Cat. No. 4997). Cell permeable. Inhibits phosphorylation of tau protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo .

catalog number base :

4998

product keywords :

downs syndrome-related kinases Dyrk1A/B inhibitors inhibits tau phosphorylation hyperphosphorylation calcineurin NFAT neural stem cells DYRK 4998,

extended description :

DYRK1A/B inhibitor; prodrug of INDY (Cat. No. 4997)

chemical name text :

(1Z)-1-(5-Acetyloxy3-ethyl-2(3H)-benzothiazolylidene)-2-propanone

formula :

C 14 H 15 NO 3 S

formula text :

C14H15NO3S

cas num :

719277-30-2

2020 USD :

183

2021 USD :

189 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage