PMX 464 | Tocris Bioscience 4996 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PMX 464

catalog :

4996

quantity :

10 mg (also 50 mg)

price :

164 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Schroeder A, Warnken U, Roth D, Klika K, Vobis D, Barnert A, et al. Targeting Thioredoxin-1 by dimethyl fumarate induces ripoptosome-mediated cell death. Sci Rep. 2017;7:43168 pubmed publisher

product information

brand :

Tocris

master code :

4996

SKU :

4996/10

product name :

PMX 464

description :

Putative inhibitor of the Trx-TrxR system; antiproliferative

target :

Other Reductase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

243.28

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system. Shown to inhibit Trx and induce a G1/S block in HT29 cells; inhibits cell proliferation in various colorectal cancer cell lines and MCF7 cells. Also elicits an anti-inflammatory response in A549 cells.

catalog number base :

4996

product keywords :

PMX464 PMX_464 antiproliferative thioredoxin reductase TrxR Trx1 inhibitors inhibits cell proliferation Thioredoxin Reductases 4996,

extended description :

Putative inhibitor of the Trx-TrxR system; antiproliferative

chemical name text :

4-(2-Benzothiazolyl)-4-hydroxy-2,5-cyclohexadien-1-one

formula :

C 13 H 9 NO 2 S

formula text :

C13H9NO2S

cas num :

485842-97-5

2020 USD :

164

2021 USD :

164 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage