Salirasib | Tocris Bioscience 4989 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Salirasib

catalog :

4989

quantity :

10 mg (also 50 mg)

price :

84 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Li L, Li M, Xu S, Bu W, Zhang M, Gu H, et al. Is Ras a potential target in treatment against cutaneous squamous cell carcinoma?. J Cancer. 2018;9:3373-3381 pubmed publisher
Lee H, Goh M, Kim J, Choi T, Kwang Lee H, Joo Na Y, et al. A systems-biological study on the identification of safe and effective molecular targets for the reduction of ultraviolet B-induced skin pigmentation. Sci Rep. 2015;5:10305 pubmed publisher

product information

brand :

Tocris

master code :

4989

SKU :

4989/10

product name :

Salirasib

description :

Ras inhibitor; also induces autophagy

target :

Ras GTPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

358.54

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of active Ras proteins. Displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also facilitates Ras degradation. Shown to induce autophagy in several human cancer cell lines.

catalog number base :

4989

product keywords :

Ras inhibitors inhibits induces autophagy Autophagy Ras GTPases 4989, Ras, GTP ase

extended description :

Ras inhibitor; also induces autophagy

chemical name text :

2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic acid

formula :

C 22 H 30 O 2 S

formula text :

C22H30O2S

cas num :

162520-00-5

2020 USD :

2021 USD :

84 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage