Salirasib | Tocris Bioscience 4989/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Salirasib

catalog :

4989/10

quantity :

10 mg

price :

93 USD

citations: 2

Reference
Li L, Li M, Xu S, Bu W, Zhang M, Gu H, et al. Is Ras a potential target in treatment against cutaneous squamous cell carcinoma?. J Cancer. 2018;9:3373-3381 pubmed publisher
Lee H, Goh M, Kim J, Choi T, Kwang Lee H, Joo Na Y, et al. A systems-biological study on the identification of safe and effective molecular targets for the reduction of ultraviolet B-induced skin pigmentation. Sci Rep. 2015;5:10305 pubmed publisher

product information

brand :

Tocris

master code :

4989

SKU :

4989/10

product name :

Salirasib

unit size :

10 mg

description :

Inhibis HIV-1 replication in vitro; nucleoside analog

target :

Ras GTPase Inhibitors

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

358.54

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Salirasib is an inhibitor of active Ras proteins. Displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also facilitates Ras degradation. Shown to induce autophagy in several human cancer cell lines.

extended description :

Ras inhibitor; also induces autophagy

chemical name text :

2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic acid

formula :

C 22 H 30 O 2 S

formula text :

C22H30O2S

cas num :

162520-00-5

USD :

Jul-22 :

93 USD

product details :

Ras inhibitor; also induces autophagy

sizes available :

10 mg (also 50 mg)