Vialinin A | Tocris Bioscience 4988 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Vialinin A

catalog :

4988

quantity :

1 mg

price :

84 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lin R, Nie J, Ren J, Liang R, Li D, Wang P, et al. USP4 interacts and positively regulates IRF8 function via K48-linked deubiquitination in regulatory T cells. FEBS Lett. 2017;591:1677-1686 pubmed publisher

product information

brand :

Tocris

master code :

4988

SKU :

4988/1

product name :

Vialinin A

description :

Inhibitor of USP4 and USP5/IsoT

target :

Deubiquitinating Enzyme Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

98%

observed molecular weight :

562.57

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50 values are 1.5, 5.9 and 22.3 M, respectively). Shows no significant inhibition of UCH-L3, USP2, and USP8 activities. Decreases release of TNF- (IC50 = 0.09 nM) from RBL-2H3 mast cells. Displays anti-cancer activity decreasing viability in human colonic carcinoma cells.

catalog number base :

4988

product keywords :

inhibitors inhibits ubquitin ubquitination ubiquitin-specific peptidase 4 USP4 USP5 isopeptidase T IsoT UCH-L1 deubiquitinating enzymes DUB TNF-a TNF-alpha TNF anti-cancer Deubiquitinating Enzymes 4988,, DUB, Deubiquitinase

extended description :

Inhibitor of USP4 and USP5/IsoT

chemical name text :

1,1 -(4,4 ,5 ,6 -Tetrahydroxy[1,1 :4 ,1 -terphenyl]-2 ,3 -diyl) benzeneacetic acid ester

formula :

C 34 H 26 O 8

formula text :

C34H26O8

cas num :

858134-23-3

2020 USD :

2021 USD :

84 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage