RN 1 dihydrochloride | Tocris Bioscience 4977/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

RN 1 dihydrochloride

catalog :

4977/10

quantity :

10 mg (also 50 mg)

price :

278 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Llewellyn G, Alvarez Carbonell D, Chateau M, Karn J, Cannon P. HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency. J Neurovirol. 2018;24:192-203 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4977

SKU :

4977/10

product name :

RN 1 dihydrochloride

Description :

LSD1 inhibitor

target :

Histone Demethylase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

452.42

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

RN 1 dihydrochloride is a potent lysine specific demethylase 1 (LSD1) inhibitor (IC50 = 70 nM). Exhibits selectivity for LSD1 over MAO-A and MAO-B (IC50 values are 0.51 and 2.79 M for MAO-A and MAO-B, respectively). Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration.

extended description :

LSD1 inhibitor

chemical name text :

1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanone dihydrochloride

formula :

C 23 H 29 N 3 O 2 .2HCl

formula text :

C23H29N3O2.2HCl

cas num :

1781835-13-9

USD :

278 USD

product details :

LSD1 inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage