BMS 688521 | Tocris Bioscience 4970/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BMS 688521

catalog :

4970/10

quantity :

10 mg

price :

301 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Xue J, Scotti E, Stoffel M. CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells. Cell Rep. 2019;28:2892-2904.e7 pubmed publisher

image

image 1 :

Cat.No. 4970 - BMS 688521 C26H19Cl2N5O4 CAS No. 893397-44-9

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4970

SKU :

4970/10

product name :

BMS 688521

description :

Potent inhibitor of the LFA-1/ICAM interaction

target :

Cell Adhesion Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

536.37

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BMS 688521 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 2.5 and 78 nM in HUVEC adhesion and mouse specific adhesion assays respectively). Inhibits eosinophil accumulation in the lungs in a mouse allergic eosinophilic lung inflammation model.

product keywords :

BMS688521 LFA-1 antagonists blocker interaction inhibitors inhibits ICAM1 lymphocyte function associated antigen intracellular adhesion molecule potent Integrins Cell Adhesion Molecules 4970,

extended description :

Potent inhibitor of the LFA-1/ICAM interaction

chemical name text :

6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4,4]non-7-yl]-3-pyridinecarboxylic acid

formula :

C26H19Cl2N5O4

formula text :

C26H19Cl2N5O4

cas num :

893397-44-9

USD :

334

USD 2025 :

301 USD

product details :

Potent inhibitor of the LFA-1/ICAM interaction

more info or order :

Tocris Bioscience product webpage