CCT 241533 dihydrochloride | Tocris Bioscience 4968 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CCT 241533 dihydrochloride

catalog :

4968

quantity :

10 mg

price :

317 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4968

SKU :

4968/10

product name :

CCT 241533 dihydrochloride

description :

Potent Chk2 inhibitor

target :

Checkpoint Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

515.41

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent Chk2 inhibitor (IC50 = 3 nM). Shows 63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide -induced DNA damage in HT29 cells. Blocks ionizing radiation-induced apoptosis of mouse thymocytes.

catalog number base :

4968

product keywords :

checkpoint kinase 2 CHK inhibitors inhibits radioprotectant potent selective Checkpoint Kinases Checkpoint Control Kinases 4968,

extended description :

Potent Chk2 inhibitor

chemical name text :

(3R,4S)-4-[[2-(5-Fluoro-2-hydroxyphenyl)-6,7-dimethoxy-4-quinazolinyl]amino]- , -dimethyl-3-pyrrolidinemethanol dihydrochloride

formula :

C 23 H 27 FN 4 O 4 .2HCl

formula text :

C23H27FN4O4.2HCl

cas num :

1962925-28-5

2020 USD :

307

2021 USD :

317 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage