CCT 241533 dihydrochloride | Tocris Bioscience 4968/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CCT 241533 dihydrochloride

catalog :

4968/10

quantity :

10 mg

price :

354 USD

product information

brand :

Tocris

master code :

4968

SKU :

4968/10

product name :

CCT 241533 dihydrochloride

unit size :

10 mg

seo description :

Potent Chk2 inhibitor

target :

Checkpoint Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

515.41

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CCT 241533 dihydrochloride is a potent Chk2 inhibitor (IC50 = 3 nM). Shows 63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide -induced DNA damage in HT29 cells. Blocks ionizing radiation-induced apoptosis of mouse thymocytes.

top caption :

Potent Chk2 inhibitor

extended description :

Potent Chk2 inhibitor

chemical name text :

(3R,4S)-4-[[2-(5-Fluoro-2-hydroxyphenyl)-6,7-dimethoxy-4-quinazolinyl]amino]- , -dimethyl-3-pyrrolidinemethanol dihydrochloride

formula :

C23H27FN4O4.2HCl

formula text :

C23H27FN4O4.2HCl

cas num :

1962925-28-5

USD :

354 USD

product details :

Potent Chk2 inhibitor

storage :

Desiccate at RT