TC-S 7001 | Tocris Bioscience 4961/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-S 7001

catalog :

4961/1

quantity :

1 mg

price :

256 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4961

SKU :

4961/1

product name :

TC-S 7001

Description :

Potent and highly selective ROCK inhibitor; orally active

target :

Rho-kinase Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

98%

observed molecular weight :

402.79

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-S 7001 (also known as BAY-549) is a potent and highly selective ROCK inhibitor (IC50 values are 0.6 and 1.1 nM for human ROCK1 and ROCK2, respectively), which exhibits 200-fold selectivity over TRK and FLT3 receptors, and 900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. TC-S 7001 reduces blood pressure in normotensive and hypertensive rats, and is orally active.

extended description :

Potent and highly selective ROCK inhibitor; orally active

chemical name text :

6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine

formula :

C 18 H 13 ClF 2 N 6 O

formula text :

C18H13ClF2N6O

cas num :

867017-68-3

USD :

256 USD

product details :

Potent and highly selective ROCK inhibitor; orally active

alt names :

Azaindole-1, BAY-549

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage