UAMC 00039 dihydrochloride | Tocris Bioscience 4954/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UAMC 00039 dihydrochloride

catalog :

4954/10

quantity :

10 mg (also 50 mg)

price :

283 USD

citations: 1

Reference
Klein Z, Takahashi H, Ma M, Stagi M, Zhou M, Lam T, et al. Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice. Neuron. 2017;95:281-296.e6 pubmed publisher

product information

brand :

Tocris

master code :

4954

SKU :

4954/10

product name :

UAMC 00039 dihydrochloride

description :

Dipeptidyl peptidase II (DPP-II) inhibitor

target :

Additional Synthetic Protease Inhibitors

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

382.76

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

UAMC 00039 dihydrochloride is a potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC50 = 0.48 nM). Exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC50 values are 78.6, 142 and 165 M, respectively). Orally available.

extended description :

Dipeptidyl peptidase II (DPP-II) inhibitor

chemical name text :

(2S)-2-Amino-4-[[(4-chlorophenyl)methyl]amino]-1-(1-piperidinyl)-1-butanone dihydrochloride

formula :

C 16 H 24 ClN 3 O.2HCl

formula text :

C16H24ClN3O.2HCl

cas num :

697797-51-6

USD :

283 USD

product details :

Dipeptidyl peptidase II (DPP-II) inhibitor

storage :

Store at -20°C